OVARIAN VOLUME - A NOVEL OUTCOME PREDICTOR FOR ASSISTED REPRODUCTION

Objective: To determine the potential of ovarian volume as a predictor of assisted reproduction outcomes. Design: Retrospective chart review . Setting: University-based assisted reproduction program. Patients: O ne hundred eighty-eight women initiating their first cycle of assisted reproduction. Interventions: None. Main Outcome Measures: Pretreatmen t transvaginal ultrasound ovarian measurements were compared with subs equent ovulation induction parameters (peak E(2), numbers of oocytes, and embryos) and cycle outcome (cancellation and pregnancy).Result: To tal ovarian volume and volume of the smallest ovary were significant v ariables predicting peak E(2) and numbers of oocytes and embryos. Tota l ovarian volume was a predictor of cycle cancellation and volume of t he smallest ovary a predictor of clinical pregnancy. Large ovarian vol umes are associated with good assisted reproductive technology outcome s whereas small ovarian volumes are associated with poor outcomes. Con clusion: Beyond maternal age, total ovarian volume, and volume of the smallest ovary are significant predictors of the success of assisted r eproductive techniques.