THE KLEIHAUER-BETKE TEST - CLINICAL UTILITY, INDICATION, AND CORRELATION IN PATIENTS WITH PLACENTAL ABRUPTION AND COCAINE USE

This study examines the indications for performing the Kleihauer-Betke (KB) test and makes recommendations for its use. Results of 523 KB te sts performed during 1993 at our hospital (Cleveland, Ohio) are review ed in conjunction with surgical pathology reports of placental finding s, obstetric records, and toxicology results. We conclude that the KB test should be performed following a positive screening test on all Rh negative mothers of Rh positive infants. Additional indications inclu de cases of maternal trauma, unexplained increased maternal alpha-feto protein levels, fetal distress with abnormal heart tracings, intrauter ine fetal death, and cases of unexplained neonatal anemia. We note tha t the KB test should not be performed to detect suspected placental ab ruption.