EXPRESSION OF ALPHA-FETOPROTEIN BY OVARIAN SERTOLI-LEYDIG CELL TUMORS- CASE-REPORT AND REVIEW OF THE LITERATURE

Authors
HAMMAD A JASNOSZ KM OLSON PR
Citation
A. Hammad et al., EXPRESSION OF ALPHA-FETOPROTEIN BY OVARIAN SERTOLI-LEYDIG CELL TUMORS- CASE-REPORT AND REVIEW OF THE LITERATURE, Archives of pathology and laboratory medicine, 119(11), 1995, pp. 1075-1079
Citations number
29
Categorie Soggetti
Pathology,"Medical Laboratory Technology","Medicine, Research & Experimental
Journal title
Archives of pathology and laboratory medicine
ISSN journal
00039985 → ACNP
Volume
119
Issue
11
Year of publication
1995
Pages
1075 - 1079
Database
ISI
SICI code
0003-9985(1995)119:11<1075:EOABOS>2.0.ZU;2-9
Abstract
A 17-year-old girl had an ovarian Sertoli-Leydig cell tumor associated with elevation of the serum alpha-fetoprotein level. On microscopic e xamination, the tumor had a predominantly spindled cellular stroma con taining open and solid tubules, focal clusters of hepatoid cells, and heterologous carcinoid. Alpha-fetoprotein was demonstrated within the hepatoid cells by immunohistochemical techniques. After surgery, serum alpha-fetoprotein level fell to normal, and the patient is still free of tumor 8 months later.