AROMATIC NUCLEOPHILIC-SUBSTITUTION REACTIONS - KINETICS OF SUBSTITUTION OF 2-CHLOROPYRIMIDINE AND 2,4,6-TRICHLORO-1,3,5-TRIAZINE BY VARIOUSNUCLEOPHILES

Authors
RAMESH A SUNDAR BS MURTI PSR
Citation
A. Ramesh et al., AROMATIC NUCLEOPHILIC-SUBSTITUTION REACTIONS - KINETICS OF SUBSTITUTION OF 2-CHLOROPYRIMIDINE AND 2,4,6-TRICHLORO-1,3,5-TRIAZINE BY VARIOUSNUCLEOPHILES, Journal of the Indian Chemical Society, 72(10), 1995, pp. 697-700
Citations number
10
Categorie Soggetti
Chemistry
Journal title
Journal of the Indian Chemical Society → ACNP
ISSN journal
00194522
Volume
72
Issue
10
Year of publication
1995
Pages
697 - 700
Database
ISI
SICI code
0019-4522(1995)72:10<697:ANR-KO>2.0.ZU;2-R
Abstract
Kinetics of substitution of 2-chloropyrimidine and 2,4,6-trichloro-1,3 ,5-triazine with a variety of nucleophiles are reported, The reactivit y pattern shows that the halogens flanked by two heterocyclic nitrogen s in a ring are displaced with facility, The reactions with pyridine o f 2,4,6-trichloropyrimidine and 2,4,6-trichloro-1,3,5-triazine are rou ted through N+ cations formed in successive displacements which explai n the overall displacement of halogens in these systems.