Aim-To investigate the quality of perinatal and infant necropsies and
assess the relation between the quality and value of this investigatio
n in different outcome groups. Methods-Cohort analysis of 540 deaths d
uring 1993 of babies between 20 weeks' gestation and one year of age b
orn to women usually resident in Wales, Cases were identified from the
All Wales Perinatal Survey. Each case was assessed to establish wheth
er the necropsy yielded clinically relevant information. The quality o
f necropsy was assessed by scoring aspects identified as being part of
the necropsy. Results-Necropsy was performed in 335 (62%) cases, and
the report was available for assessment in 314 cases. The quality of n
ecropsy was below the minimum standard in 46% (143/314) of cases. The
highest quality necropsies were carried out on fetal deaths at 20 to 2
3 weeks' gestation (12% (10/85) below standard), compared with 65% (87
/133) below standard on stillbirths and 68% (21/31) on sudden unexpect
ed infant death. Overall, 42% (131/314) of necropsies were performed i
n a regional paediatric pathology centre including 88% (76/88) of feta
l deaths, 23% (31/133) of still-births and 30% (29/96) of infant death
s. The quality score for the necropsy performed in a regional centre f
ailed to achieve the minimum acceptable score in 8% (11/131) of cases
compared with 72% (132/182) for those done elsewhere. The cause of dea
th was detected by necropsy in 17% (52/314) of cases. The quality of n
ecropsy was significantly higher when the cause of death was revealed
than when nothing new was found. Conclusions-The overall quality of th
e perinatal and infant necropsy is poor. This is regrettable as valuab
le information can be revealed frequently by a good quality necropsy.
Adherence to Guidelines for Postmortem Reports recently published by t
he Royal College of Pathologists should improve the situation.