HEART-TRANSPLANTATION FOR CHAGAS CARDIOMYOPATHY

Authors
BLANCHE C ALEKSIC I TAKKENBERG JJM CZER LSC FISHBEIN MC TRENTO A
Citation
C. Blanche et al., HEART-TRANSPLANTATION FOR CHAGAS CARDIOMYOPATHY, The Annals of thoracic surgery, 60(5), 1995, pp. 1406-1409
Citations number
12
Categorie Soggetti
Surgery,"Cardiac & Cardiovascular System
Journal title
The Annals of thoracic surgery → ACNP
ISSN journal
00034975
Volume
60
Issue
5
Year of publication
1995
Pages
1406 - 1409
Database
ISI
SICI code
0003-4975(1995)60:5<1406:HFCC>2.0.ZU;2-4
Abstract
We present 2 patients who underwent orthotopic heart transplantation f or end-stage Chagas' cardiomyopathy. Despite immunosuppressive therapy , postoperative prophylaxis with nifurtimox appeared to prevent Trypan osoma cruzi reactivation. Neither patient has shown signs of Chagas' m yocarditis, and both are clinically well 12 and 72 months after transp lantation. The successful outcome of our patients suggests that heart transplantation is a reasonable therapeutic option in patients with en dstage Chagas' cardiomyopathy.