Wd. Obrien et al., GUIDED TISSUE REGENERATION USING A BIODEGRADABLE BARRIER MEMBRANE FORNEW ATTACHMENT - A CLINICAL, HISTOLOGIC, AND HISTOMETRIC STUDY IN DOGS, The International journal of periodontics & restorative dentistry, 15(5), 1995, pp. 447-461
Although nonbiodegradable barrier membranes have proven partially succ
essful in achieving regeneration of lost periodontium through the prin
ciples of guided tissue regeneration, their use requires a second surg
ical procedure for their removal. The results of a study, in which a b
iodegradable collagen membrane was used to treat dehiscence defects in
dogs, are presented. The membrane was an effective barrier to the dow
ngrowth of gingival epithelium during the early stages of healing and
tended to increase the regeneration of new cementum and connective tis
sue attachment. It was also biocompatible and biodegradable.