STRUCTURE OF THE GENE ENCODING THE MOUSE PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE RECEPTOR

Authors
AINO H HASHIMOTO H OGAWA N NISHINO A YAMAMOTO K NOGI H NAGATA S BABA A
Citation
H. Aino et al., STRUCTURE OF THE GENE ENCODING THE MOUSE PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE RECEPTOR, Gene, 164(2), 1995, pp. 301-304
Citations number
24
Categorie Soggetti
Genetics & Heredity
Journal title
Gene → ACNP
ISSN journal
03781119
Volume
164
Issue
2
Year of publication
1995
Pages
301 - 304
Database
ISI
SICI code
0378-1119(1995)164:2<301:SOTGET>2.0.ZU;2-M
Abstract
The PACAP-R gene, encoding the mouse pituitary adenylate cyclase-activ ating polypeptide receptor (PACAP-R), has been isolated and its struct ural organization has been determined. PACAP-R spans more than 50 kb a nd is divided into 18 exons. PACAP-R contains two alternative exons en coding the putative third intracellular loop, as found in the rat PACA P-R. The proximal promoter region is highly G+C rich and lacks an appa rent TATA box, but contains a CCAAT box and two potential Spl-binding sites.