Intracavernosal injection therapy has consistently produced erections
in 60% to 70% of patients in whom it is tried. About 70% of patients e
nter long-term therapy and there is a dropout rate of 20% to 50% withi
n the first year. The most effective current regimen is a mixture of p
apaverine-phentolamine and prostaglandin E1, that also seems to have a
relatively low incidence of priapism and fibrous nodule formation. Pa
tient education is vitally important to the success of a program. Pati
ent satisfaction rates are high.