ORIGINS OF SIMIAN IMMUNODEFICIENCY VIRUS-INFECTION IN MACAQUES AT THENEW-ENGLAND-REGIONAL-PRIMATE-RESEARCH-CENTER

Authors
MANSFIELD KG LERCHE NW GARDNER MB LACKNER AA
Citation
Kg. Mansfield et al., ORIGINS OF SIMIAN IMMUNODEFICIENCY VIRUS-INFECTION IN MACAQUES AT THENEW-ENGLAND-REGIONAL-PRIMATE-RESEARCH-CENTER, Journal of medical primatology, 24(3), 1995, pp. 116-122
Citations number
25
Categorie Soggetti
Zoology,"Veterinary Sciences
Journal title
Journal of medical primatology → ACNP
ISSN journal
00472565
Volume
24
Issue
3
Year of publication
1995
Pages
116 - 122
Database
ISI
SICI code
0047-2565(1995)24:3<116:OOSIVI>2.0.ZU;2-1
Abstract
A cohort of rhesus macaques (Macaca mulatta), obtained from the Califo rnia Regional Primate Research Center (CRPRC) and necropsied in 1970-7 2 with lesions suggestive of simian immunodeficiency virus (SIV) infec tion, was identified at the New England Regional Primate Research Cent er (NERPRC). Polymerase chain reaction (PCR) DNA sequence analysis, an d in situ hybridization were used to confirm the presence of SIV nucle ic acids. This represents the earliest case of SIV infection at the NE RPRC and suggests a common source for present day SIV isolates.