Thymic nurse cells are multicellular complexes located in the subcorti
cal area of the thymus of all avian, mammalian and amphibian species i
nvestigated so far. Since their first description in 1980 many studies
have been carried out to characterize their morphological and functio
nal properties. The purpose of this review is to summarize recent morp
hological as well as functional analyses of chicken thymic nurse cells
which suggest a role of these cell complexes in T cell selection.