Clinicians' ratings of the negative syndrome of schizophrenia are high
ly correlated with the rate and duration of the patient's pauses. To t
est the degree to which pausing provides the cue for clinicians' impre
ssions we selected audio recordings of interviews with schizophrenic p
atients who showed moderate levels of negative signs and, through the
use of a computerized digital editor, transformed the recordings by ei
ther doubling or halving the duration of all of the patient's pauses.
Other aspects of the patients' speech were unchanged. Ratings of flat
affect were changed by the editing: reduced pause samples were seen as
less flat and increased pause samples as flatter. Ratings of mood wer
e not significantly changed. These results suggest that neuropsycholog
ical factors that interfere with fluent speech may play a role in the
pathogenesis of the negative syndrome. In addition, the edited tapes p
rovide helpful materials for training clinicians to assess moods and a
ffects.