SPECIFIC CLEAVAGE OF SYNTHETIC RENIN SUBSTRATE BY MOUSE GAMMA-NERVE GROWTH-FACTOR

Authors
UDDIN M BEG OU
Citation
M. Uddin et Ou. Beg, SPECIFIC CLEAVAGE OF SYNTHETIC RENIN SUBSTRATE BY MOUSE GAMMA-NERVE GROWTH-FACTOR, Journal of protein chemistry, 14(7), 1995, pp. 621-625
Citations number
19
Categorie Soggetti
Biology
Journal title
Journal of protein chemistry → ACNP
ISSN journal
02778033
Volume
14
Issue
7
Year of publication
1995
Pages
621 - 625
Database
ISI
SICI code
0277-8033(1995)14:7<621:SCOSRS>2.0.ZU;2-3
Abstract
Results of the present investigation indicate that mouse gamma-nerve g rowth factor (gamma-NGF), which belongs to the kallikrein family of pr oteins, specifically cleaves the Phe-His bond of a synthetic renin sub strate and exhibits rat-tonin-like activity. Since other mouse kallikr eins do not cleave this bond, gamma-NGF may play a regulatory role in the generation of antiogensin-II.