THE EPIDERMAL GROWTH-FACTOR TRANSFORMING GROWTH-FACTOR-ALPHA FAMILY AND THEIR RECEPTORS

Authors
BROWN KD
Citation
Kd. Brown, THE EPIDERMAL GROWTH-FACTOR TRANSFORMING GROWTH-FACTOR-ALPHA FAMILY AND THEIR RECEPTORS, European journal of gastroenterology & hepatology, 7(10), 1995, pp. 914-922
Citations number
NO
Categorie Soggetti
Gastroenterology & Hepatology
Journal title
European journal of gastroenterology & hepatology → ACNP
ISSN journal
0954691X
Volume
7
Issue
10
Year of publication
1995
Pages
914 - 922
Database
ISI
SICI code
0954-691X(1995)7:10<914:TEGTGF>2.0.ZU;2-#
Abstract
Cytokines and growth factors act as intercellular signalling molecules which control cellular functions during development and in response t o injury or infection. The epidermal growth factor (EGF) family is an expanding group of structurally related polypeptides that regulate cel l proliferation, migration and differentiation, via tyrosine kinase re ceptors on target cells. This chapter reviews recent developments in t he characterization of EGF family members and their receptors.