BASIC ACTIONS OF TRANSFORMING GROWTH-FACTOR-ALPHA AND RELATED PEPTIDES

Authors
COFFEY RJ GANGAROSA LM DAMSTRUP L DEMPSEY PJ
Citation
Rj. Coffey et al., BASIC ACTIONS OF TRANSFORMING GROWTH-FACTOR-ALPHA AND RELATED PEPTIDES, European journal of gastroenterology & hepatology, 7(10), 1995, pp. 923-927
Citations number
NO
Categorie Soggetti
Gastroenterology & Hepatology
Journal title
European journal of gastroenterology & hepatology → ACNP
ISSN journal
0954691X
Volume
7
Issue
10
Year of publication
1995
Pages
923 - 927
Database
ISI
SICI code
0954-691X(1995)7:10<923:BAOTGA>2.0.ZU;2-Y
Abstract
Transforming growth factor-alpha (TGF-alpha) and related peptides have been implicated in a wide range of biological activities, including c ell growth, differentiation and acid inhibition. This chapter reviews the roles of TGF-alpha in the stomach, the insights gained into the ac tion of the TGF-alpha a Family of growth factors from the study of pol arized epithelial cells and the confirmation of events mediated by the epidermal growth factor receptor (EGFR) by the study of mice in which the EGFR has been disrupted by homologous recombination.