Ia. Seledtsov et al., MULTIPLE ALIGNMENT OF BIOPOLYMER SEQUENCES BASED ON SEARCH FOR STATISTICALLY SIGNIFICANT COMMON REGIONS, Molecular biology, 29(5), 1995, pp. 600-610
The algorithm proposed for alignment of biopolymer sequences is based
on search for and inclusion of regions with statistically significant
similarity in the aligned pair. It is implemented in a PC program for
multiple sequence alignment over a given similarity tree, which yields
high-quality results in a short time and with low RAM requirements.