THE CHEMOTACTIC EFFECT OF PHLEBOTOMUS-DUBOSCQI (DIPTERA, PSYCHODIDAE)SALIVARY-GLAND LYSATES TO MURINE MONOCYTES

Authors
ANJILI CO MBATI PA MWANGI RW GITHURE JI OLOBO JO ROBERT LL KOECH DK
Citation
Co. Anjili et al., THE CHEMOTACTIC EFFECT OF PHLEBOTOMUS-DUBOSCQI (DIPTERA, PSYCHODIDAE)SALIVARY-GLAND LYSATES TO MURINE MONOCYTES, Acta Tropica, 60(2), 1995, pp. 97-100
Citations number
13
Categorie Soggetti
Tropical Medicine",Parasitiology
Journal title
Acta Tropica → ACNP
ISSN journal
0001706X
Volume
60
Issue
2
Year of publication
1995
Pages
97 - 100
Database
ISI
SICI code
0001-706X(1995)60:2<97:TCEOP(>2.0.ZU;2-K
Abstract
The possibility that salivary gland lysates of Phlebotomus duboscqi ar e able to attract vertebrate monocytes was investigated. In vitro stud ies showed that salivary gland lysates of P. duboscqi, the vector of L eishmania major in Kenya, are chemotactic to mouse peritoneal monocyte s. This attraction of monocytes by vector salivary gland lysates may f orm part of the mechanisms through which sandfly saliva ensures succes sful parasitization of macrophages in a susceptible host by Leishmania parasites.