RIA was used to study the quantitative content in the blood serum of t
hyrotropic (TTH), thyroid (total thyroxine (T4), free thyroxine, triio
dothyronine (T3) hormones and thyroxine-binding capacity of blood plas
ma proteins in 30 patients with brain concussion from the first to the
12th day of disease. The patients' hormonal profile was characterized
by normal characteristics of TTH, depression of the transport organic
phase of thyroid metabolism with a decrease of the T4 concentration,
a reduction of the thyroxine-binding capacity of plasma protein, and s
imultaneous activation of the peripheral stage of iodine metabolism wi
th excess accumulation in the blood of active hormones - free thyroxin
e and T3. The data obtained deepen our understanding of the pathogenes
is of craniocerebral injury (CCI). The neuroendocrine syndrome identif
ied is specific for mild CCI. It can be used as a differential diagnos
tic criterion for expert medical evaluation purposes.