BIOCHEMICAL ASPECTS OF IRON-METABOLISM, T RANSPORT AND REGULATION

Authors
GOLDENBERG H SCHEIBER B
Citation
H. Goldenberg et B. Scheiber, BIOCHEMICAL ASPECTS OF IRON-METABOLISM, T RANSPORT AND REGULATION, Wiener Klinische Wochenschrift, 107(22), 1995, pp. 669-676
Citations number
102
Categorie Soggetti
Medicine, General & Internal
Journal title
Wiener Klinische Wochenschrift → ACNP
ISSN journal
00435325
Volume
107
Issue
22
Year of publication
1995
Pages
669 - 676
Database
ISI
SICI code
0043-5325(1995)107:22<669:BAOITR>2.0.ZU;2-8
Abstract
Iron metabolism in man is controlled by homeostatic mechanisms mainly based on intracellular regulation of iron uptake, utilisation and stor age. Despite impressive accumulation of knowledge in recent years, the question how iron actually passes cellular membranes and how this tra nsport process is regulated remains largely unanswered. Various models and hypotheses are discussed in context with other well established f eatures of iron homeostasis.