CALEDONIN, A NATURAL PEPTIDE BOLAPHILE WITH ZN-II AND CU-I COMPLEXINGPROPERTIES FROM THE TUNICATE DIDEMNUN RODRIGUESI

Authors
VAZQUEZ MJ QUINOA E RIGUERA R OCAMPO A IGLESIAS T DEBITUS C
Citation
Mj. Vazquez et al., CALEDONIN, A NATURAL PEPTIDE BOLAPHILE WITH ZN-II AND CU-I COMPLEXINGPROPERTIES FROM THE TUNICATE DIDEMNUN RODRIGUESI, Tetrahedron letters, 36(48), 1995, pp. 8853-8856
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
48
Year of publication
1995
Pages
8853 - 8856
Database
ISI
SICI code
0040-4039(1995)36:48<8853:CANPBW>2.0.ZU;2-7
Abstract
Caledonin (1) is a modified peptide isolated from the marine tunicate Didemnun rodriguesi. Caledonin comprises a central L-phenylalanine res idue connected via its amino group to (S)-3-amino-5-mercaptopentanoic acid (a new sulfur-containing beta-amino acid), and by its carboxyl gr oup to a six membered cycloguanidine moiety, bearing an n-octyl chain. Caledonin is a natural bolaphile which strongly binds Zn-II and Cu-I ions.