KINETIC RESOLUTION OF (1RS,2SR)-2-(HYDROXYMETHYL)CYCLOPENTANOL BY A BIOCATALYTIC TRANSESTERIFICATION USING LIPASE PS

Authors
WEIDNER J THEIL F SCHICK H
Citation
J. Weidner et al., KINETIC RESOLUTION OF (1RS,2SR)-2-(HYDROXYMETHYL)CYCLOPENTANOL BY A BIOCATALYTIC TRANSESTERIFICATION USING LIPASE PS, Tetrahedron : asymmetry, 5(4), 1994, pp. 751-754
Citations number
12
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
5
Issue
4
Year of publication
1994
Pages
751 - 754
Database
ISI
SICI code
0957-4166(1994)5:4<751:KRO(BA>2.0.ZU;2-Q
Abstract
The kinetic resolution of (1RS,2SR)-2-(hydroxymethyl)cyclopentanol [(1 RS,2SR)-1] by a sequential lipase-catalyzed transesterification with v inyl acetate in organic solvents in the presence of lipase from Pseudo monas cepacia (lipase PS) is described. The results are compared with data for the resolution of two structurally related 1,3-diols.