Infection remains a major cause of morbidity and mortality following C
SF shunt procedures. In this study 198 shunt procedures carried out fr
om January 1981 to December 1992 in a series of 81 infants (less than
6 months old) were retrospectively analyzed for possible risk factors;
The overall surgical infection rate was 7.8%, with 15 infections occu
rring in 14 patients (17.2%). No significant difference in the sate of
infections was found in relation to sex, birth weight, gestational ag
e, and type of shunt procedure (primary insertion/revision). The occur
rence of other infections during the period of shunt surgery did not i
nfluence the infection risk either. Intraventricular hemorrhage and ce
ntral nervous system infections as causes of the hydrocephalus were fo
und to correlate with septic risk. Young age (less than 6 months) seem
s to represent the main risk factor, and this is related both to the i
mmunologic deficiency and to the particular features of residential ba
cterial flora in this age group.