M. Gardeback et al., NITRIC-OXIDE IMPROVES HYPOXEMIA FOLLOWING REPERFUSION EDEMA AFTER PULMONARY THROMBOENDARTERECTOMY, British Journal of Anaesthesia, 75(6), 1995, pp. 798-800
A patient underwent pulmonary thromboendarterectomy for chronic, major
-vessel thromboembolic pulmonary hypertension. After operation the pat
ient developed reperfusion oedema and hypoxaemia which was treated suc
cessfully with inhalation of nitric oxide. Before operation, the respo
nse to inhaled nitric oxide was characterized by a slight reduction in
pulmonary vascular resistance but without improvement in gas exchange
. The postoperative improvement in oxygenation after inhalation of nit
ric oxide contrasted sharply with the preoperative reaction.