QUARTZ-CRYSTAL MICROBALANCE DETECTION OF VIBRIO-CHOLERAE O139 SEROTYPE

Authors
CARTER RM MEKALANOS JJ JACOBS MB LUBRANO GJ GUILBAULT GG
Citation
Rm. Carter et al., QUARTZ-CRYSTAL MICROBALANCE DETECTION OF VIBRIO-CHOLERAE O139 SEROTYPE, Journal of immunological methods, 187(1), 1995, pp. 121-125
Citations number
19
Categorie Soggetti
Immunology
Journal title
Journal of immunological methods → ACNP
ISSN journal
00221759
Volume
187
Issue
1
Year of publication
1995
Pages
121 - 125
Database
ISI
SICI code
0022-1759(1995)187:1<121:QMDOVO>2.0.ZU;2-A
Abstract
A piezoelectric (PZ) quartz crystal microbalance (QCM) biosensor for t he rapid detection of Vibrio cholerae serotype O139 has been developed . The antibody to this serotype was immobilized on the gold transducer surface of a 10 MHz AT cut PZ crystal. Solutions containing known ant igen concentrations were then incubated for 1 h on the antibody-bound transducer. The biosensor was able to detect 10(5) cells per ml of O13 9 versus a background of O1 (Ogawa) serotype.