ANTIOXIDANT FUNCTION OF MELANIN IN BLACK FUNGI

Authors
JACOBSON ES HOVE E EMERY HS
Citation
Es. Jacobson et al., ANTIOXIDANT FUNCTION OF MELANIN IN BLACK FUNGI, Infection and immunity, 63(12), 1995, pp. 4944-4945
Citations number
20
Categorie Soggetti
Immunology,"Infectious Diseases
Journal title
Infection and immunity → ACNP
ISSN journal
00199567
Volume
63
Issue
12
Year of publication
1995
Pages
4944 - 4945
Database
ISI
SICI code
0019-9567(1995)63:12<4944:AFOMIB>2.0.ZU;2-Z
Abstract
1,8-Dihydroxynaphthalene melanin in Wangiella dermatitidis and Alterna ria alternata was titrated in vivo with the oxidants permanganate, hyp ochlorite, and H2O2. Melanized strains neutralized more oxidant and wi thstood higher concentrations of permanganate and hypochlorite than al bino strains did, H2O2 killing required 1,000-fold higher concentratio ns, and melanin did not protect W. dermatitidis against H2O2.