PURPOSE: To follow up the growth of renal angiomyolipomas (AMLs). MATE
RIALS AND METHODS: Patients with known AML (n = 55) were divided into
three groups on the basis of initial clinical and computed tomographic
(CT) findings: group 1, isolated AML (n = 43); group 2, multiple AMLs
without tuberous sclerosis (TS) (n = 6); group 3, multiple AMLs with
TS (n = 6). Follow-up ultrasonography (US) and CT were performed in 55
and 31 patients, respectively. Growth of the AMLs (n = 59) was evalua
ted on the basis of area on initial and follow-up images. RESULTS: Mea
n percentage growth was 17%, 128%, and 47%, and mean growth rate per y
ear was 5%, 22%, and 18% in groups 1, 2, and 3, respectively. New rena
l lesions were noted in three patients in groups 1 and 2, but no new l
esions were detected in group 3, because of the large number of AMLs.
New extrarenal lesions were observed in four, two, and three patients
in groups 1, 2, and 3, respectively. No correlation was found between
percentage of fatty tissue and growth rate. CONCLUSION: Multiple AMLs
show more growth than solitary AMLs.