THE BIOSYNTHESIS OF VALANIMYCIN - FURTHER EVIDENCE FOR THE INTERMEDIACY OF A HYDROXYLAMINE IN N-N BOND FORMATION

Authors
PARRY RJ LI WY
Citation
Rj. Parry et Wy. Li, THE BIOSYNTHESIS OF VALANIMYCIN - FURTHER EVIDENCE FOR THE INTERMEDIACY OF A HYDROXYLAMINE IN N-N BOND FORMATION, Journal of the Chemical Society, Chemical Communications, (8), 1994, pp. 995-996
Citations number
23
Categorie Soggetti
Chemistry
Journal title
Journal of the Chemical Society, Chemical Communications → ACNP
ISSN journal
00224936
Issue
8
Year of publication
1994
Pages
995 - 996
Database
ISI
SICI code
0022-4936(1994):8<995:TBOV-F>2.0.ZU;2-X
Abstract
New evidence supporting the hypothesis that the biosynthesis of the N- N bond of the antibiotic valanimycin involves the reaction of a hydrox ylamine with an amine to give a hydrazine is obtained by partial purif ication of a hydroxylamine-forming enzyme and by successful incorporat ion experiments with a postulated hydrazine intermediate.