Toxicoses associated with products which are derived from plants and t
hen used as insecticides and skin care/grooming aids on animals, are r
eviewed. These include pyrethrins, pyrethroids, rotenone, pennyroyal o
il, D-limonene, linalool and melaleuca oil. Poisoning is uncommon and
generally results from exposure to concentrations stronger than that r
ecommended by the manufacturer. Pyrethrins and pyrethroids may cause e
xcessive salivation, tremors, ataxia, depression, hyperexcitability/hy
peractivity, seizures, dyspnea and rarely death of the animal. Ingesti
on of rotenone by licking may induce vomiting in dogs and cats. D-Limo
nene may cause excess salivation, marked hypothermia, shivering and at
axia in cats, and dermal exposure of cats to a spray containing linalo
ol, D-limonene and piperonyl butoxide at 5 and 10 times normal concent
ration has caused depression and recumbency lasting for several days.
This was followed by recovery without treatment. Melaleuca oil has bee
n associated with ataxia, incoordination, weakness, tremors and depres
sion. Bathing with a mild detergent, treatment of associated signs, an
d providing supportive care are usually adequate therapy for these tox
icoses. An exception is pennyroyal oil which is hepatotoxic.