Hj. Prompeler et al., TRANSVAGINAL SONOGRAPHY OF MYOMETRIAL INVASION DEPTH IN ENDOMETRIAL CANCER, Acta obstetricia et gynecologica Scandinavica, 73(4), 1994, pp. 343-346
The myometrial invasion depth of endometrial cancer is an important pr
ognostic factor. The preoperative assessment is decisive for the appro
priate surgical treatment. In 96 patients with endometrial cancer, the
myometrial invasion depth (greater than 50% or less than 50%) was mea
sured preoperatively using transvaginal sonography (TVS). The sonograp
hic results were compared to the histopathological findings. A sensiti
vity of 93% was obtained for invasion depths greater than 50%. The pre
dictive value of an invasion depth less than 50% was 93% as well. In 1
6% of the cases the invasion depth was overestimated while, in only 3%
it was underestimated. The diagnostic accuracy was 81%. Forty-five pa
tients were examined preceding a diagnostic dilatation and curettage a
nd fifty-one were examined following a diagnostic dilatation and curet
tage. The diagnostic accuracy in both groups was equivalent. Using tra
nsvaginal sonography, the spread of cancer to the cervix was observed
in five of the seven cases in which it was postoperatively confirmed.
TVS is a valuable, non-invasive diagnostic method for patients with en
dometrial cancer. When the TVS data are combined with results from oth
er preoperative tests, the prognostic information obtained provides a
useful basis in choosing the appropriate therapy.