Ja. Verbraecken et al., OBSTRUCTIVE SLEEP HYPOPNEA SYNDROME IN A PATIENT WITH MARFAN-SYNDROMETREATED WITH OXYGEN-THERAPY, Respiration, 62(6), 1995, pp. 355-358
A patient with Marfan's syndrome and obstructive sleep hypopnea syndro
me is reported. She had complained about insomnia, tiredness and hyper
somnolence lasting 2 years. A complete nightly polysomnography reveale
d 94 obstructive hypopneas (the hypopnea index was 12.85) and no obstr
uctive apneas. Presumably an increased laxity of the pharyngeal wall w
as responsible for the phenomenon. A therapy with CPAP was started, bu
t was not tolerated by the patient. Oxygen therapy on the other hand t
urned out to be effective and well tolerated.