During a ten year observation period it was found that scar formation
after thoracic surgery is influenced by various factors: metabolism, o
perative technique and factors of a general nature. On the basis of th
ese findings, a study was carried out to investigate the effect of the
scar-specific Contractubex gel (Merz + Co., D-Frankfurt/Main), contai
ning 10% onion extract, 50 U sodium heparin per g of gel and 1% allant
oin, in the treatment of children who underwent thoracic surgery and t
o evaluate its effect oil scar development Before and during the six-m
onth treatment period, both macromorphology and scar colour were asses
sed; furthermore, a global evaluation of the therapeutic result was ma
de. Additionally, the scars were characterized after a six-month treat
ment-free follow-up period. The results of 38 Contractubex-treated and
27 untreated patients were compared. in the treated scars, the global
evaluation of the therapeutic result was better than in the untreated
scars. in the Contractubex group, the rating was ''good'' and ''very
good'' in 84% of cases, as compared to 59% of the untreated cases. in
the treated group, the increase in scar size was markedly lower than i
n the untreated patients. The treated scars showed a tendency towards
quicker paling than the untreated scars. in the treated group, the con
version of primary physiological scars to unphysiological scars (hyper
trophic or keloidal scars) was less frequent than in the untreated gro
up. The tolerability of the product was very good in 37 of the 38 trea
ted patients, and good in one patient. All scar-specific effects of Co
ntractubex continued to persist after the end of treatment.