Objective: Our goal was to compare 3D phase contrast (PC) echo planar
imaging (EPI) MRA of the carotid and vertebral arteries with conventio
nal 3D PC in volunteers and patients. Materials and Methods: The carot
id arteries of 12 volunteers were imaged with conventional and EPI 3D
PC sequences. The visibility for each of seven carotid and four verteb
ral segments was qualitatively assessed. Signal intensity and homogene
ity determinations were performed on the source images. Three patients
with known carotid artery disease were also imaged with the same prot
ocol. Results: EPI reduced 3D PC data acquisition time from 459 to 32
s (factor of 15). Both techniques permitted full assessment of the com
mon carotid artery, the bifurcation, as well as the proximal internal
carotid artery (ICA), external carotid artery (ECA), and vertebral art
eries. Visualization of the distal ICA/ECA and vertebral arteries was
inferior with EPI compared with the conventional acquisition. In all p
atients, lesions as established by X-ray angiography were seen to equa
l advantage with both techniques. Conclusion: EPI 3D PC MRA renders di
agnostic images of the proximal carotid system. The considerable reduc
tion in data acquisition time must be weighed against poorer image qua
lity.