CHRONIC MYELOPATHY ASSOCIATED WITH HUMAN HERPESVIRUS-6

Authors
MACKENZIE IRA CARRIGAN DR WILEY CA
Citation
Ira. Mackenzie et al., CHRONIC MYELOPATHY ASSOCIATED WITH HUMAN HERPESVIRUS-6, Neurology, 45(11), 1995, pp. 2015-2017
Citations number
13
Categorie Soggetti
Clinical Neurology
Journal title
Neurology → ACNP
ISSN journal
00283878
Volume
45
Issue
11
Year of publication
1995
Pages
2015 - 2017
Database
ISI
SICI code
0028-3878(1995)45:11<2015:CMAWHH>2.0.ZU;2-M
Abstract
Human herpesvirus-6 (HHV-6) is implicated in a variety of neurologic d iseases. We report a previously healthy elderly woman with progressive spastic paraparesis. At autopsy the spinal cord showed widespread dem yelination, axonal loss, and chronic inflammation. HHV-6 DNA was ampli fied, using polymerase chain reaction, from spinal cord tissue, and gl ial cells were immunoreactive with an HHV-6 antibody. These findings s uggest that HHV-6 may cause myelopathy.