Bs. Dean et al., COMPARISON OF MEDICATION ERRORS IN AN AMERICAN AND A BRITISH HOSPITAL, American journal of health-system pharmacy, 52(22), 1995, pp. 2543-2549
Medication errors in a hospital in the United States and a hospital in
the United Kingdom were compared. The study was conducted in wards wi
th a high oral-drug-related workload in two large university hospitals
. The U.S. hospital was studied in August 1993 and the U.K. hospital i
n May and June 1993. The U.S. hospital had a typical unit dose drug di
stribution system, and the U.K. hospital had the ward-based system com
monly used in that country, in which a pharmacist visits each ward sev
eral times daily and reviews each patient's medication chart. The medi
cation chart is used by the physician to order drugs and obviates the
need for transcription of orders. A disguised-observation technique wa
s used to determine frequencies and types of medication errors. Medica
tion errors were identified retrospectively in the U.S. hospital by co
mparing the observer's notes with the original drug orders made in the
patient's chart by the physician. In the U.K. hospital, identificatio
n of errors took place concurrently; as doses were administered, they
were compared with the orders on the medication chart. In the U.S. and
U.K. hospitals, 919 and 2756 opportunities for error were observed, r
espectively. The medication error rate in the U.S. hospital was 6.9% (
95% confidence interval [CI], 5.2% to 8.5%), significantly higher than
the 3.0% rate observed in the U.K. hospital (95% CI, 2.4% to 3.7%) (9
5% CI for the difference, 2.1% to 5.7%). Omitted doses and incorrect d
oses were the most common types of errors in the U.K. hospital; incorr
ect doses and unordered doses were the most common types in the U.S. h
ospital. An American hospital with a unit dose distribution system had
a significantly higher medication error rate than a British hospital
with a ward-based supply system.