Primary systemic amyloidosis is a rare cause of vertebral collapse. We
describe a patient who presented multiplecollapsed vertebrae. Magneti
c resonance imaging (MRI) demonstrated a diffuse bone marrow abnormali
ty. A diffuse low signal throughout the vertebral bodies on T1 and T2
weighted spin-echo images were observed. A bone biopsy confirmed the s
uspected diagnosis of vertebral involvementby amyloid. MR imaging can
be of interest to evaluate the bone spreading of a known amyloidosis a
nd to help in the diagnosis of amyloidosis in the case of non traumati
cal vertebral fractures.