Objective. To assess ultrasound findings in patients with rheumatoid a
rthritis affecting the hand and wrist compared to normal volunteers. D
esign. Metacarpophalangeal and carpal articulations were imaged ultras
onically. Two readers reviewed static images for synovial, cartilagino
us, and bony abnormalities using severity and probability scales. Ultr
asound findings were correlated with disease activity. Patients. Ten n
ormal volunteers and 29 patients with known rheumatoid arthritis. Resu
lts. Synovial abnormalities and erosions were most commonly identified
in the rheumatoid hand and wrist (p<0.01). Criteria used for normal a
nd abnormal cartilage did not predict normal and disease states. Signi
ficant differences in synovial abnormalities and erosions were observe
d between the inactive and mildly active disease groups as well as the
active and mildly active disease groups (p<0.01). Conclusion. Ultraso
und can detect abnormalities of the hand and wrist in patients with rh
eumatoid arthritis compared to normal volunteers. Normal articular ana
tomy is well demonstrated ultrasonically.