URINE STROMAL TUMOR RESEMBLING OVARIAN SE X-CORD TUMOR - CASE-REPORT

Citation
Lc. Horn et He. Stegner, URINE STROMAL TUMOR RESEMBLING OVARIAN SE X-CORD TUMOR - CASE-REPORT, Der Pathologe, 16(6), 1995, pp. 421-425
Citations number
26
Categorie Soggetti
Pathology
Journal title
ISSN journal
01728113
Volume
16
Issue
6
Year of publication
1995
Pages
421 - 425
Database
ISI
SICI code
0172-8113(1995)16:6<421:USTROS>2.0.ZU;2-F
Abstract
Uterine tumors resembling sex-cord ovarian structures are exceptionall y rare. Clement and Scully divided them into two groups. The first gro up includes cases with less than 50 % and the second with more than 50 % sex-cord elements. Group one tumors show a higher incidence of recu rrences. We report a case of a 54-year-old women with a partly retrope ritoneal, cystic tumor 7 . 6 . 6 cm. Histologically, sex-cord differen tiation of more than 50 % was seen with positive immunostaining agains t vimentin, desmin and focally against myoglobin and cytokeratines. Th e reaction against EMA, CEA and S 100 was negative. The patient was tr eated by abdominal hysterectomy with bilateral salpingooovorectomy. Sh e shows no evidence of disease 2.3 years after the initial surgery. Ba sed on the light microscopic features and immunohistochemical pattern, the tumor was interpreted as arising from the endometrial stromal cel ls or multipotential uterine mesenchyme that showed diverse differenti ation toward ovarian sex-cord stroma and uterine smooth muscle with in terspersed stromal cell clusters.