CREUTZFELDT-JAKOB-DISEASE - WHAT IS THE R OLE OF MAGNETIC-RESONANCE TOMOGRAPHY

Creutzfeldt-Jakob disease (CJD) is a rare, but fatal and transmissible brain disease. The clinical diagnosis is based upon progressing demen tia, myoclonic jerks and characteristic EEG changes, but it is difficu lt to diagnose and not only in the early phase of the disease. Cerebra l biopsy is reserved for individual selected cases and contested becau se of the darger of contamination from instruments and potential trans mission. We report three patients with histologically confirmed MRI is a valuable tool for the diagnosis of this disease.