EFFECT OF SCREENING OF DONORS FOR ANTIBODIES TO HEPATITIS-C VIRUS BY 2ND-GENERATION ASSAY ON INCIDENCE OF HCV INFECTION IN ACUTE-LEUKEMIA

Authors
KAWATANI T SUOU T ENDO A TAJIMA F KAWASAKI H
Citation
T. Kawatani et al., EFFECT OF SCREENING OF DONORS FOR ANTIBODIES TO HEPATITIS-C VIRUS BY 2ND-GENERATION ASSAY ON INCIDENCE OF HCV INFECTION IN ACUTE-LEUKEMIA, HEPATOLOGY RESEARCH, 4(3), 1995, pp. 139-141
Citations number
8
Categorie Soggetti
Gastroenterology & Hepatology
Journal title
HEPATOLOGY RESEARCH → ACNP
ISSN journal
13866346
Volume
4
Issue
3
Year of publication
1995
Pages
139 - 141
Database
ISI
SICI code
1386-6346(1995)4:3<139:EOSODF>2.0.ZU;2-S
Abstract
We examined the incidence of hepatitis C virus (HCV) infection in 42 p atients with acute leukemia before and after blood donor screening for the HCV Ab using the first-generation assay and the second-generation assay. Although 14 (93%) of the 15 patients before screening and 6 (5 0%) of the 12 patients after screening by the first-generation assay b ecame seropositive for HCV RNA, none of the 15 patients became seropos itive after screening by the second-generation assay. These findings i ndicate that the second-generation assay is effective in preventing HC V infection in multitransfused patients with acute leukemia.