SANDIMMUN (CYCLOSPORINE-A) TREATMENT OF N EPHROTIC-TYPE CHRONIC GLOMERULONEPHRITIS

Authors
MUKHIN NA TAREEVA IY KRASNOVA TN SHILOV YM MIROSHNICHENKO NG
Citation
Na. Mukhin et al., SANDIMMUN (CYCLOSPORINE-A) TREATMENT OF N EPHROTIC-TYPE CHRONIC GLOMERULONEPHRITIS, Terapevticeskij arhiv, 67(8), 1995, pp. 13-15
Citations number
NO
Categorie Soggetti
Medicine, General & Internal
Journal title
Terapevticeskij arhiv → ACNP
ISSN journal
00403660
Volume
67
Issue
8
Year of publication
1995
Pages
13 - 15
Database
ISI
SICI code
0040-3660(1995)67:8<13:S(TONE>2.0.ZU;2-S
Abstract
Sandimmun (ciclosporin A) treatment of chronic glomerulonephritis with nephrotic syndrome in a dose 2.5-5 mg/kg for 6-10 months relieved nep hrotic syndrome in 2 and resulted in clinical improvement in other 2 o f 4 patients treated. In 3 cases the patients failed previous therapy with high-dose corticosteroids and cytostatics. The drug reduced prote inuria, elevated serum levels of albumin and total protein, had low ne phrotoxicity.