NONSPECIFIC BRONCHIAL REACTIVITY IN PREAS THMA AND ASTHMA AND ITS ACUPUNCTURE-INDUCED CHANGES

The development of nonspecific bronchial hypersensitivity and hyperrea ctivity in bronchial asthma and effectiveness of its correction with a cupuncture were investigated in 152 patients with asthma and preasthma . 94 of them were subjected to acupuncture. The authors employed a com plex of diagnostic methods with determination of 241 parameters proces sed later with the use of systemic modelling. Bronchial hypersensitivi ty as indicated by the response to acetylcholine was related to impair ed coordination of bronchomotor tone regulating systems: parasympathet ic part of the autonomic nervous system, eosinophylic and monocytic br onchial inflammation, glucocorticoid homeostatic alterations. The corr ective role of acupuncture consists in reduction of nonspecific bronch ial hyperreactivity, normalization of blood acetylcholine, resensitiza tion of cell beta-adrenergic receptors, elevation of mean concentratio ns of 11-OCS and T-lymphocytes.