COMPOSITION AND STRUCTURES OF TRIGLYCERID ES OF HUMAN-MILK AND SOME BASE COMPONENTS FOR INFANT MILK FORMULAS

Following HPLC separation of human milk triglycerides with a silver-lo aded ion exchange and an RP-18-phase column, the 50 substantial fracti ons obtained were characterized by gas chromatography of triglycerides and fatty acid methyl esters as well as by the analysis of intramolec ular distribution on a reduced scale using ethyl magnesium bromide. Ex ploitation of all data available resulted in the detailed structures o f 106 triglycerides, representing 81 g/100 g human milk fat. A substit ute for producing infant milk formulas should be adapted to the compos ition and fatty acid distribution of those 14 substantial triglyceride s which are present in human milk fat with more than 1 g/100 g, amount ing to a total of 42 g/100 g. Among several fats and oils analyzed, on ly lard and a recent product were found to contain palmitic acid also predominantly in the 2-position. Therefore, other base components woul d require a directed fractionation and/or interesterification to be be st adapted to human milk fat.