Wb. Geven et al., FOLLOW-UP IN NEONATAL EXTRACORPOREAL MEMBRANE-OXYGENATION (ECMO), International journal of artificial organs, 18(10), 1995, pp. 584-588
In 34 survivors of the first 43 ECMO patients from our institution bef
ore discharge to another hospital or home an EEG, BAER, Head Ultrasono
graphy, cerebral CT scan, Dubowitz score and ophthalmological inspecti
on were performed. At one year of age Mental Developmental Index of th
e Bayley scales, Motor Quotient as well as pulmonary and neurological
status were assessed. In 29 patients follow-up took place in our hospi
tal. In 17 of them (59%) all tests before discharge were normal, 2 pat
ients (7%) showed an abnormal BAER, an additional 5 patients (17%) had
abnormal EEG and 2 patients (7%) had abnormal HUS in combination with
abnormal cerebral CT scan. In 19 patients (33%) the Dubowitz score wa
s abnormal at discharge. At one year of age neurological status was no
rmal in 25 (86%) patients, respiratory status was normal in 22 (76%) a
nd Mental Development Index was > 80 in 23 of the patients (79%). A si
gnificant correlation between Mental Development Index and Motor Quoti
ent was found r=0.50, p=0.0065. It is concluded that more than one abn
ormal neurophysiological test before discharge may identify patients w
ith additional risks for adverse outcome and that the respiratory stat
us influenced psychomotor development at one year of age.