A DUTCH POPULATION STUDY OF THE STR LOCI HUMTHO1, HUMFES FPS, HUMVWA31/1 AND HUMF13A1, CONDUCTED FOR FORENSIC PURPOSES/

Citation
M. Sjerps et al., A DUTCH POPULATION STUDY OF THE STR LOCI HUMTHO1, HUMFES FPS, HUMVWA31/1 AND HUMF13A1, CONDUCTED FOR FORENSIC PURPOSES/, International journal of legal medicine, 108(3), 1995, pp. 127-134
Citations number
35
Categorie Soggetti
Pathology
ISSN journal
09379827
Volume
108
Issue
3
Year of publication
1995
Pages
127 - 134
Database
ISI
SICI code
0937-9827(1995)108:3<127:ADPSOT>2.0.ZU;2-H
Abstract
We report on a Dutch population study of the STR loci HUMTHO1, HUMFES/ FPS, HUMVWA31/1, and HUMF13A1, in which we used multiplex amplificatio n and automated fragment detection. Genotype and allele frequencies sh owed no deviation from Hardy-Weinberg and linkage equilibrium. The imp roved Bonferroni procedure was used to combine the results of several tests. The power of discrimination of a complete profile exceeded 0.99 98. We compared the allele frequencies in the Dutch sample to the freq uencies in other populations using a biplot to visualize alleles and p opulations simultaneously. The Dutch sample was similar to most other Caucasian samples. The data demonstrate that the genetic systems in th is report are a valuable tool for forensic identity testing in The Net herlands.