Tw. Gyorkos et al., COMPLIANCE WITH ANTIMALARIAL CHEMOPROPHYLAXIS AND THE SUBSEQUENT DEVELOPMENT OF MALARIA - A MATCHED CASE-CONTROL STUDY, The American journal of tropical medicine and hygiene, 53(5), 1995, pp. 511-517
Citations number
31
Categorie Soggetti
Public, Environmental & Occupation Heath","Tropical Medicine
To determine if there is a difference in compliance with antimalarial
chemoprophylaxis between febrile travelers with and without malaria, 1
57 patients with malaria, a history of fever, and recent travel to a m
alaria-endemic area were compared with 157 matched controls. Antimalar
ial prophylaxis had been taken by 48% of all patients. Chemoprophylaxi
s use was correlated with region and purpose of travel. Cases were les
s Likely to have taken prophylaxis (53%) than controls (76%) (odds rat
io = 0.35, confidence interval = 0.27, 0.73), even after controlling f
or region of travel, purpose of travel, and previous exposure to malar
ia. Chemoprophylaxis was effective in reducing malaria risk. Travel ag
ents and health practitioners should provide all travelers to malaria-
endemic areas with adequate information about chemoprophylaxis and its
importance.