COMPLIANCE WITH ANTIMALARIAL CHEMOPROPHYLAXIS AND THE SUBSEQUENT DEVELOPMENT OF MALARIA - A MATCHED CASE-CONTROL STUDY

Citation
Tw. Gyorkos et al., COMPLIANCE WITH ANTIMALARIAL CHEMOPROPHYLAXIS AND THE SUBSEQUENT DEVELOPMENT OF MALARIA - A MATCHED CASE-CONTROL STUDY, The American journal of tropical medicine and hygiene, 53(5), 1995, pp. 511-517
Citations number
31
Categorie Soggetti
Public, Environmental & Occupation Heath","Tropical Medicine
ISSN journal
00029637
Volume
53
Issue
5
Year of publication
1995
Pages
511 - 517
Database
ISI
SICI code
0002-9637(1995)53:5<511:CWACAT>2.0.ZU;2-8
Abstract
To determine if there is a difference in compliance with antimalarial chemoprophylaxis between febrile travelers with and without malaria, 1 57 patients with malaria, a history of fever, and recent travel to a m alaria-endemic area were compared with 157 matched controls. Antimalar ial prophylaxis had been taken by 48% of all patients. Chemoprophylaxi s use was correlated with region and purpose of travel. Cases were les s Likely to have taken prophylaxis (53%) than controls (76%) (odds rat io = 0.35, confidence interval = 0.27, 0.73), even after controlling f or region of travel, purpose of travel, and previous exposure to malar ia. Chemoprophylaxis was effective in reducing malaria risk. Travel ag ents and health practitioners should provide all travelers to malaria- endemic areas with adequate information about chemoprophylaxis and its importance.