Cg. Lee et Bo. Palsson, CONTINUOUS MEDIUM PERFUSION LEADS TO LONG-TERM CELL VIABILITY AND OXYGEN PRODUCTION IN HIGH-DENSITY PHOTOBIOREACTORS, Biotechnology letters, 17(11), 1995, pp. 1149-1154
A light-emitting diode-based photobioreactor (LED-based PER) operated
in a continuous perfusion mode with a perfusion rate of 3 to 6 reactor
volumes a day supports high-density algal cultures, of cell concentra
tions up to 4-10(9) cells/mL, or 25 g/L. The oxygen production rate at
its peak was 13 to 15 mmol/(L . h). Continuous medium perfusion allow
ed for longterm stable oxygen production, while oxygen production in b
atch mode ceased when stationary phase was reached.