BIOTRANSFORMATIONS OF AROMATIC DINITRILES USING RHODOCOCCUS-EQUI CELLS

Authors
MARTINKOVA L OLSOVSKY P PREPECHALOVA I KREN V
Citation
L. Martinkova et al., BIOTRANSFORMATIONS OF AROMATIC DINITRILES USING RHODOCOCCUS-EQUI CELLS, Biotechnology letters, 17(11), 1995, pp. 1219-1222
Citations number
11
Categorie Soggetti
Biothechnology & Applied Migrobiology
Journal title
Biotechnology letters → ACNP
ISSN journal
01415492
Volume
17
Issue
11
Year of publication
1995
Pages
1219 - 1222
Database
ISI
SICI code
0141-5492(1995)17:11<1219:BOADUR>2.0.ZU;2-C
Abstract
Short incubation (1 - 5 h) of aromatic dinitriles with resting cells o f Rhodococcus equi A4 produces the corresponding cyano amides in 48 - 81 % yield. The substrate reactivity decreases in order 1,4- greater t han or equal to 1,3- > 1,2-disubstitution. Prolonged treatment (20 - 5 0 h) is needed to achieve the conversion to acid or for transformation of the second cyano group.