Objective: To review common rheumatologic disorders that affect elderl
y patients and emphasize the unique diagnostic and therapeutic challen
ges inherent in the management of rheumatologic diseases in this age-g
roup, Design: We summarize our approach to treatment and management of
specific rheumatologic problems in geriatric patients and discuss per
tinent studies from the literature, Results: Among the spectrum of rhe
umatologic disorders frequently encountered in the elderly population
are polymyalgia rheumatica, fibromyalgia, giant cell arteritis, crysta
lline arthropathies (gout and pseudogout), and degenerative joint dise
ase, The initial manifestations of these rheumatologic diseases in eld
erly patients may differ from the typical findings in younger patients
, Geriatric patients may have nonspecific complaints, a decline in phy
sical function, or even confusion, Because of physiologic changes asso
ciated with aging and a decrease in functional reserves, elderly patie
nts are susceptible to adverse effects of pharmacologic therapy (inclu
ding nonsteroidal anti-inflammatory medications, corticosteroids, narc
otic analgesics, allopurinol, and colchicine), Clinicians should be al
ert for such problems as hepatotoxicity and occult gastrointestinal bl
ood loss, Comorbid conditions such as cardiovascular disease and cogni
tive impairment may complicate management strategies and may limit the
goals of both surgical intervention and rehabilitation programs in el
derly patients, Conclusion: Rheumatologic disorders in geriatric patie
nts pose special challenges to primary-care physicians, In the selecti
on of optimal pharmacologic and nonpharmacologic therapeutic modalitie
s, clinicians should focus on maintaining or improving the patient's q
uality of life and level of independent function.