S. Pritlovecarson et al., EVALUATION OF GUIDED TISSUE REGENERATION IN THE TREATMENT OF PAIRED, PERIODONTAL DEFECTS, British Dental Journal, 179(10), 1995, pp. 388-394
The aim of the present study was to compare guided tissue regeneration
with conventional surgery in matched periodontal defects within the s
ame subject. Twenty pairs of sites in nine subjects were treated. Surg
ery was performed at both test and control sites on the same visit. Ra
ndom allocation was not performed until all preparation and root instr
umentation had been completed. Test defects were covered with e-PTFE m
embranes (Gore-Tex) and secured with sutures. Membranes were removed a
fter 5-6 weeks with a second surgical procedure, whereas the control s
ites were not re-operated. At 12 months probing depth reductions were
significantly greater at the Gore-Tex treated sites (P < 0.05) but no
difference in probing attachment level gains were found when compared
with conventional flap surgery.