EPR STUDY OF SPERMINE INTERACTION WITH MULTILAMELLAR PHOSPHATIDYLCHOLINE LIPOSOMES

Authors
MOMO F WISNIEWSKA A STEVANATO R
Citation
F. Momo et al., EPR STUDY OF SPERMINE INTERACTION WITH MULTILAMELLAR PHOSPHATIDYLCHOLINE LIPOSOMES, Biochimica et biophysica acta. Biomembranes, 1240(1), 1995, pp. 89-94
Citations number
26
Categorie Soggetti
Biology,Biophysics
Journal title
Biochimica et biophysica acta. Biomembranes → ACNP
ISSN journal
00052736
Volume
1240
Issue
1
Year of publication
1995
Pages
89 - 94
Database
ISI
SICI code
0005-2736(1995)1240:1<89:ESOSIW>2.0.ZU;2-A
Abstract
The interaction of spermine with egg-yolk phosphatidylcholine liposome s was investigated. The EPR spin labeling technique evidenced that spe rmine induces modifications of some membrane functions of biological i nterest like water permeability and is a possible modulator of diffusi on processes for charged and polar molecules. The association constant for a hypothesized complex between spermine and the phosphate group o f phosphatidylcholine was evaluated by enzymatic methods.